NOT MEDICAL ADVICE

GHRP-2

Estimated Market Price
$16 $40
Estimated for 5–10 mg vial · Based on verified supplier pricing
Potent growth hormone releasing peptide. Stimulates rapid GH pulses, supports collagen synthesis, fat metabolism, and sleep quality.
How it works

The most potent ghrelin-receptor peptide for triggering growth hormone release, producing stronger GH and IGF-1 spikes than GHRP-6. Also stimulates appetite through the same ghrelin pathway.

Growth Hormone

Performance

What to Expect
Week 1–2 Strong GH surge per dose; increased hunger and sleep depth. Strong hunger spike post-injection; sleep quality way up.
Week 3–4 IGF-1 rising steadily; recovery between sessions improving. Faster recovery; muscles feel harder after workouts.
Week 5–8 Body composition shifting; lean mass gains with fat reduction. Leaner and more muscular; body recomposition visible.
Week 9–12 Peak secretagogue response; labs recommended for titration. Peak results; strength and recovery at their best.

Verified Suppliers

For research purposes only. These suppliers have been independently verified by PepSpace. We do not process sales directly.

PepSpace is not affiliated with any listed supplier
Protocol & Dosage
Typical Dosage 100–300 mcg SC, 1–3 times daily
Administration Subcutaneous injection, Intravenous
Schedule 1–3x daily; before meals and/or before bed
Protocol Duration Cycled use
Half-Life ~25 minutes
Side Effects & Safety
Tolerability Profile Mild

Generally well tolerated; side effects are mild and transient

Common Side Effects

  • Injection site rednessmost users
  • Mild hunger increase (less than GHRP-6)some users
  • Water retentionsome users

Less Common

  • Cortisol elevation (less than GHRP-6)occasional
  • Joint stiffnessoccasional
  • Headacheoccasional
  • Fatigueoccasional

Rare / Serious

  • Prolactin elevationrare

Discontinue If

  • Carpal tunnel symptoms (hand numbness)
  • Signs of elevated blood sugar
  • Persistent edema

Contraindications

  • Active cancer or tumors
  • Diabetic retinopathy
  • Pregnancy or breastfeeding

Data note: More selective than GHRP-6 with less hunger stimulation and lower cortisol impact, but less selective than ipamorelin.

Always consult a qualified healthcare professional before use. This information is for research reference only and does not constitute medical advice.

Ask about GHRP-2
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How to Apply

1

Gather

Peptide vial, BAC water, alcohol swabs, insulin syringe

2

Sanitize

Wipe tops of both vials with alcohol swabs

3

Draw

Pull 1–2 mL of BAC water into syringe

4

Add Water

Release water slowly along vial wall, not directly on powder

5

Swirl

Roll between palms until dissolved. Never shake.

6

Store

Refrigerate 2–8°C, use within 30 days

Frequently Asked Questions

Yes. Bacteriostatic water (BAC water) is required to reconstitute lyophilized (freeze-dried) peptides. It contains 0.9% benzyl alcohol which prevents bacterial growth, keeping your reconstituted peptide safe for multiple uses over up to 30 days.

Unreconstituted: store at -20°C (freezer) for long-term, or 2–8°C (fridge) for short-term. After reconstitution: always refrigerate at 2–8°C and use within 30 days. Keep away from direct sunlight.

Results vary by individual and protocol. In research settings, measurable effects are typically observed within 1–4 weeks depending on the specific peptide, dosage, and application. Consult a qualified professional for guidance.

Verified suppliers typically include a full third-party COA verifying purity (99%+), identity, and sterility. We recommend only sourcing from vendors that provide batch-specific testing data.

We list verified suppliers above that have been independently reviewed for product quality, testing transparency, and shipping reliability. Always verify COA data before sourcing.

Compound Profile

Scientific data & classification for GHRP-2

Also Known As Growth Hormone Releasing Peptide-2, KP-102, Pralmorelin
Classification Hexapeptide · Growth Hormone Secretagogue
Sequence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula C₄₅H₅₅N₉O₆
Molecular Weight 817.97 Da
CAS Number 158861-67-7
Half-Life ~25 minutes
Origin Synthetic hexapeptide, second-generation GHRP
Administration Subcutaneous injection, Intravenous
Status Approved in Japan (Pralmorelin) - GH deficiency diagnostics
Mechanism of Action The most potent ghrelin-receptor peptide for triggering growth hormone release, producing stronger GH and IGF-1 spikes than GHRP-6. Also stimulates appetite through the same ghrelin pathway.
Research Overview Growth Hormone Releasing Peptide-2 (GHRP-2), also known by its pharmaceutical name pralmorelin, is a synthetic hexapeptide growth hormone secretagogue that represents the second generation of GHRP development, offering enhanced potency over GHRP-6 while retaining many of the same pharmacological characteristics. Developed through structure-activity optimization of the original GHRP scaffold, GHRP-2 incorporates D-alanine at the first position and D-β-naphthylalanine at the second position, substitutions that improved binding affinity at the growth hormone secretagogue receptor (GHS-R1a) and produced the most potent GH-releasing response among the classical hexapeptide GHRPs. GHRP-2 achieved a notable milestone as one of the few growth hormone secretagogues to receive regulatory approval for clinical use - it was approved in Japan under the name pralmorelin as a diagnostic agent for growth hormone deficiency, administered intravenously and measuring the subsequent GH response to determine pituitary somatotroph reserve. The pharmacological profile of GHRP-2 shares the core characteristics of ghrelin receptor agonism but with some distinguishing features compared to GHRP-6. GHRP-2 produces a stronger peak GH response per microgram administered, stimulates appetite through hypothalamic ghrelin pathway activation (though potentially somewhat less than GHRP-6), and elevates cortisol and prolactin to a modest degree. Long-term administration studies in animal models have demonstrated sustained increases in GH pulsatility and IGF-1 levels without evidence of receptor desensitization or tachyphylaxis over several weeks, suggesting maintained efficacy with repeated dosing. Research into GHRP-2's effects beyond growth hormone release has revealed interesting cardioprotective properties - studies have shown protection against ischemia-reperfusion injury in cardiac tissue and reduction of fibrosis markers, though these effects are less well-characterized than those of hexarelin, which is considered the most cardioprotective member of the GHRP family.

Citations

Published findings on GHRP-2 from peer-reviewed journals.

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