NOT MEDICAL ADVICE

Selank

Estimated Market Price
$79.99 $94.99
Based on verified supplier pricing for research-grade compounds
Anxiolytic nootropic peptide for focus, mental clarity, and stress resilience. Clean cognitive enhancement without stimulants.
How it works

Boosts GABA signaling and BDNF levels in the brain to reduce anxiety without causing drowsiness or brain fog. Also has immune-modulating effects inherited from its tuftsin backbone.

Focus & Cognition

bestseller

What to Expect
Days 1–3 Subtle anxiolytic effect; mild calming without drowsiness. A calm settles in; you feel less reactive to stress.
Week 1 GABA modulation stabilizes; noticeable stress resilience. Anxiety fades; social situations feel easier.
Week 2 BDNF upregulation improving focus and emotional regulation. Thinking feels clearer; you can focus longer without drifting.
Week 3–4 Peak anxiolytic and cognitive benefits; assess continuation. Steady emotional balance; worry and overthinking reduced.

Verified Suppliers

For research purposes only. These suppliers have been independently verified by PepSpace. We do not process sales directly.

PepSpace is not affiliated with any listed supplier
Protocol & Dosage
Typical Dosage 200–600 mcg/day intranasal
Administration Intranasal, Subcutaneous injection
Schedule Once or twice daily, AM preferred
Protocol Duration 2–4 weeks
Half-Life Minutes (nasal administration extends effective duration)
Side Effects & Safety
Tolerability Profile Favorable

Very well tolerated; side effects are rare and mild

Common Side Effects

  • Mild nasal irritation (intranasal route)most users

Less Common

  • Slight drowsinessoccasional
  • Temporary fatigueoccasional
  • Mild headacheoccasional

Rare / Serious

  • Dry mouthrare
  • Mild allergic rhinitisrare

Discontinue If

  • Worsening anxiety or paradoxical agitation
  • Persistent nasal bleeding
  • Severe allergic reaction (facial swelling, hives)

Contraindications

  • Pregnancy or breastfeeding
  • Severe anxiety disorders (unmonitored)
  • Known hypersensitivity to tuftsin-derived peptides

Data note: Approved anxiolytic in Russia (2009). No sedation, cognitive impairment, or dependence reported — unlike benzodiazepines.

Always consult a qualified healthcare professional before use. This information is for research reference only and does not constitute medical advice.

Ask about Selank
Send us a message

Call us
+1 (518) 327-4392
Business hours
Monday – Friday 9:00 AM – 6:00 PM EST
Saturday 10:00 AM – 2:00 PM EST
Sunday Closed

You can also reach us via or .

How to Apply

1

Gather

Peptide vial, BAC water, alcohol swabs, insulin syringe

2

Sanitize

Wipe tops of both vials with alcohol swabs

3

Draw

Pull 1–2 mL of BAC water into syringe

4

Add Water

Release water slowly along vial wall, not directly on powder

5

Swirl

Roll between palms until dissolved. Never shake.

6

Store

Refrigerate 2–8°C, use within 30 days

Frequently Asked Questions

Yes. Bacteriostatic water (BAC water) is required to reconstitute lyophilized (freeze-dried) peptides. It contains 0.9% benzyl alcohol which prevents bacterial growth, keeping your reconstituted peptide safe for multiple uses over up to 30 days.

Unreconstituted: store at -20°C (freezer) for long-term, or 2–8°C (fridge) for short-term. After reconstitution: always refrigerate at 2–8°C and use within 30 days. Keep away from direct sunlight.

Results vary by individual and protocol. In research settings, measurable effects are typically observed within 1–4 weeks depending on the specific peptide, dosage, and application. Consult a qualified professional for guidance.

Verified suppliers typically include a full third-party COA verifying purity (99%+), identity, and sterility. We recommend only sourcing from vendors that provide batch-specific testing data.

We list verified suppliers above that have been independently reviewed for product quality, testing transparency, and shipping reliability. Always verify COA data before sourcing.

Compound Profile

Scientific data & classification for Selank

Also Known As TP-7, Selanc
Classification Heptapeptide · Nootropic / Anxiolytic
Sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula C₃₃H₅₇N₁₁O₉
Molecular Weight 751.87 Da
CAS Number 129954-34-3
Half-Life Minutes (nasal administration extends effective duration)
Origin Synthetic analog of tuftsin (immunomodulatory peptide) with Pro-Gly-Pro extension
Administration Intranasal, Subcutaneous injection
Status Approved in Russia - anxiolytic / nootropic
Mechanism of Action Boosts GABA signaling and BDNF levels in the brain to reduce anxiety without causing drowsiness or brain fog. Also has immune-modulating effects inherited from its tuftsin backbone.
Research Overview Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1990s through a deliberate structure-activity relationship approach to create an anxiolytic compound with improved pharmacological properties. The peptide was designed by conjugating a synthetic analog of tuftsin - a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) cleaved from the Fc region of immunoglobulin G that plays a role in innate immunity - with a Pro-Gly-Pro tripeptide extension at the C-terminus. This modification was critical because native tuftsin is rapidly degraded by aminopeptidases in vivo, whereas the PGP extension provides resistance to enzymatic cleavage and extends the biological activity window. Selank received regulatory approval in Russia in 2009 as an intranasal anxiolytic and nootropic agent, making it one of the few peptide-based anxiolytics to achieve clinical approval anywhere in the world. The compound's anxiolytic mechanism involves modulation of GABAergic neurotransmission - specifically, it has been shown to influence the expression of genes encoding GABA-A receptor subunits, shifting the subunit composition toward a configuration associated with reduced anxiety. Concurrently, selank increases the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus, an effect shared with classical antidepressants but achieved without the typical onset delay. Importantly, unlike benzodiazepines and other GABAergic anxiolytics, selank produces its anti-anxiety effects without causing sedation, cognitive impairment, muscle relaxation, or dependence - a pharmacological profile that has generated significant interest in Western neuropharmacology research. The peptide's dual identity as both an immunomodulatory and neurotropic compound reflects the growing recognition of neuroimmune interactions, with studies demonstrating that selank can normalize IL-6 and TNF-α expression while simultaneously enhancing enkephalin and serotonin metabolism in the brain.

Citations

Published findings on Selank from peer-reviewed journals.

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