NOT MEDICAL ADVICE

Thymalin

Estimated Market Price
$89.99 $104.99
Based on verified supplier pricing for research-grade compounds
Thymus-derived immune bioregulator. Restores T-cell balance, enhances NK cell activity, and demonstrated reduced mortality in longitudinal human studies.
How it works

Restores thymus-driven immune function by maturing T-cells and rebalancing the ratio of helper to suppressor T-cells. Essentially recalibrates your adaptive immune system toward a younger, more responsive state.

Immune Support

Longevity

What to Expect
Days 1–2 T-cell maturation signaling initiated; immune priming begins. Nothing noticeable yet; immune priming underway.
Days 3–5 T-helper/suppressor ratio normalizing; phagocytic activity rising. May notice slightly more energy and resilience.
Days 6–8 Immune function measurably enhanced; infection resistance up. Getting over minor illnesses faster; feeling more robust.
Days 9–10 Cycle completing; immune benefits persist weeks post-cycle. Immune function feeling stronger; cycle completing.

Verified Suppliers

For research purposes only. These suppliers have been independently verified by PepSpace. We do not process sales directly.

PepSpace is not affiliated with any listed supplier
Protocol & Dosage
Typical Dosage 5–10 mg IM daily
Administration Intramuscular injection
Schedule Once daily IM for 5–10 day cycles
Protocol Duration 5–10 days per cycle
Half-Life Short
Side Effects & Safety
Tolerability Profile Favorable

Very well tolerated; side effects are rare and mild

Common Side Effects

  • Injection site rednessmost users

Less Common

  • Mild allergic reactionoccasional
  • Temporary fatigueoccasional
  • Headacheoccasional

Discontinue If

  • Severe allergic reaction
  • Signs of autoimmune activation
  • Persistent fever

Contraindications

  • Active autoimmune disease (unmonitored)
  • Organ transplant recipients
  • Pregnancy or breastfeeding

Data note: Approved in Russia for immune modulation. Dipeptide thymic extract with decades of clinical use. Very well tolerated.

Always consult a qualified healthcare professional before use. This information is for research reference only and does not constitute medical advice.

Ask about Thymalin
Send us a message

Call us
+1 (518) 327-4392
Business hours
Monday – Friday 9:00 AM – 6:00 PM EST
Saturday 10:00 AM – 2:00 PM EST
Sunday Closed

You can also reach us via or .

How to Apply

1

Gather

Peptide vial, BAC water, alcohol swabs, insulin syringe

2

Sanitize

Wipe tops of both vials with alcohol swabs

3

Draw

Pull 1–2 mL of BAC water into syringe

4

Add Water

Release water slowly along vial wall, not directly on powder

5

Swirl

Roll between palms until dissolved. Never shake.

6

Store

Refrigerate 2–8°C, use within 30 days

Frequently Asked Questions

Yes. Bacteriostatic water (BAC water) is required to reconstitute lyophilized (freeze-dried) peptides. It contains 0.9% benzyl alcohol which prevents bacterial growth, keeping your reconstituted peptide safe for multiple uses over up to 30 days.

Unreconstituted: store at -20°C (freezer) for long-term, or 2–8°C (fridge) for short-term. After reconstitution: always refrigerate at 2–8°C and use within 30 days. Keep away from direct sunlight.

Results vary by individual and protocol. In research settings, measurable effects are typically observed within 1–4 weeks depending on the specific peptide, dosage, and application. Consult a qualified professional for guidance.

Verified suppliers typically include a full third-party COA verifying purity (99%+), identity, and sterility. We recommend only sourcing from vendors that provide batch-specific testing data.

We list verified suppliers above that have been independently reviewed for product quality, testing transparency, and shipping reliability. Always verify COA data before sourcing.

Compound Profile

Scientific data & classification for Thymalin

Also Known As Thymalin, EW Peptide
Classification Dipeptide · Immunomodulator
Sequence Glu-Trp
Molecular Formula C₁₆H₁₉N₃O₆
Molecular Weight 333.34 Da
CAS Number 62305-08-2
Half-Life Short
Origin Synthetic dipeptide based on thymus extract
Administration Intramuscular injection
Status Approved in Russia - immunodeficiency conditions
Mechanism of Action Restores thymus-driven immune function by maturing T-cells and rebalancing the ratio of helper to suppressor T-cells. Essentially recalibrates your adaptive immune system toward a younger, more responsive state.
Research Overview Thymalin is a synthetic dipeptide bioregulator with the sequence Glu-Trp (glutamic acid-tryptophan) developed by Professor Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology as part of a comprehensive research program into short peptide bioregulators that spans over four decades of investigation in Russian medical science. The concept underlying thymalin and other Khavinson peptides proposes that short peptides (2-4 amino acids) derived from organ-specific tissue extracts can selectively regulate gene expression and protein synthesis in the tissues from which they originate, functioning as endogenous molecular signals that maintain tissue homeostasis and decline with age. Thymalin was originally derived from peptide fractions extracted from calf thymus tissue and subsequently identified as the synthetic dipeptide Glu-Trp that reproduced the immunomodulatory activity of the whole extract. The peptide's proposed mechanism involves direct interaction with DNA - studies using atomic force microscopy, circular dichroism spectroscopy, and molecular modeling have suggested that short peptides can bind to specific nucleotide sequences in the minor groove of DNA, potentially modulating chromatin conformation and gene transcription. In the case of thymalin, this interaction is proposed to upregulate genes involved in T-lymphocyte maturation and differentiation. Clinical studies conducted primarily in Russia have reported that thymalin treatment normalizes T-cell subpopulation ratios (CD4/CD8), enhances phagocytic activity of neutrophils and macrophages, stimulates thymic hormone production, and improves cell-mediated immune responses in patients with various immunodeficiency conditions. A notable long-term observational study by Khavinson followed elderly patients treated with thymalin (and the pineal peptide epithalon) over a 15-year period, reporting significant reductions in all-cause mortality and improvements in biomarkers of aging.

Citations

Published findings on Thymalin from peer-reviewed journals.

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