NOT MEDICAL ADVICE

Hexarelin

Estimated Market Price
$16 $40
Estimated for 5–10 mg vial · Based on verified supplier pricing
Most potent GHRP available. Maximum growth hormone stimulation with unique cardioprotective benefits. Strategic cycling recommended for sustained results.
How it works

The strongest GH-releasing peptide in its class, activating ghrelin receptors on the pituitary. Uniquely also protects heart tissue from damage and fibrosis independently of its growth hormone effects.

Growth Hormone

Performance

What to Expect
Week 1–2 Strongest GHRP-class GH surge; deep sleep improvement. Deepest sleep you've had in years; hunger may spike.
Week 3–4 Cardioprotective signaling active; recovery accelerating. Recovery feels supercharged; cardiovascular endurance improving.
Week 5–8 IGF-1 optimized; lean mass and cardiac function improving. Getting leaner and stronger; heart feels healthier.
Week 9–12 Full GH and cardioprotective benefits; lab assessment advised. Peak physical performance; body and energy transformed.

Verified Suppliers

For research purposes only. These suppliers have been independently verified by PepSpace. We do not process sales directly.

PepSpace is not affiliated with any listed supplier
Protocol & Dosage
Typical Dosage 100–300 mcg SC, 1–3 times daily
Administration Subcutaneous injection, Intravenous
Schedule 1–3x daily; before meals and/or before bed
Protocol Duration Cycled use
Half-Life ~70 minutes
Side Effects & Safety
Tolerability Profile Moderate

Notable side effects likely; manageable with proper awareness

Common Side Effects

  • Injection site rednessmost users
  • Mild hunger increasesome users
  • Water retentionsome users
  • Flushingsome users

Less Common

  • Cortisol elevationoccasional
  • Prolactin elevationoccasional
  • Joint stiffnessoccasional
  • Headacheoccasional
  • Tingling or numbnessoccasional

Rare / Serious

  • Cardiac effects (unique GH-independent cardiac binding)rare

Discontinue If

  • Heart palpitations or chest pain
  • Carpal tunnel symptoms (hand numbness)
  • Persistent edema

Contraindications

  • Active cancer or tumors
  • Cardiovascular disease or arrhythmia
  • Pregnancy or breastfeeding

Data note: Most potent GHRP but also least selective. Unique cardiac receptor binding (CD36) warrants caution in those with heart conditions. Rapid desensitization limits use beyond 4-8 weeks.

Always consult a qualified healthcare professional before use. This information is for research reference only and does not constitute medical advice.

Ask about Hexarelin
Send us a message

Call us
+1 (518) 327-4392
Business hours
Monday – Friday 9:00 AM – 6:00 PM EST
Saturday 10:00 AM – 2:00 PM EST
Sunday Closed

You can also reach us via or .

How to Apply

1

Gather

Peptide vial, BAC water, alcohol swabs, insulin syringe

2

Sanitize

Wipe tops of both vials with alcohol swabs

3

Draw

Pull 1–2 mL of BAC water into syringe

4

Add Water

Release water slowly along vial wall, not directly on powder

5

Swirl

Roll between palms until dissolved. Never shake.

6

Store

Refrigerate 2–8°C, use within 30 days

Frequently Asked Questions

Yes. Bacteriostatic water (BAC water) is required to reconstitute lyophilized (freeze-dried) peptides. It contains 0.9% benzyl alcohol which prevents bacterial growth, keeping your reconstituted peptide safe for multiple uses over up to 30 days.

Unreconstituted: store at -20°C (freezer) for long-term, or 2–8°C (fridge) for short-term. After reconstitution: always refrigerate at 2–8°C and use within 30 days. Keep away from direct sunlight.

Results vary by individual and protocol. In research settings, measurable effects are typically observed within 1–4 weeks depending on the specific peptide, dosage, and application. Consult a qualified professional for guidance.

Verified suppliers typically include a full third-party COA verifying purity (99%+), identity, and sterility. We recommend only sourcing from vendors that provide batch-specific testing data.

We list verified suppliers above that have been independently reviewed for product quality, testing transparency, and shipping reliability. Always verify COA data before sourcing.

Compound Profile

Scientific data & classification for Hexarelin

Also Known As Examorelin, HEX, Hexarelin Acetate
Classification Hexapeptide · Growth Hormone Secretagogue
Sequence His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula C₄₇H₅₈N₁₂O₆
Molecular Weight 887.04 Da
CAS Number 140703-51-1
Half-Life ~70 minutes
Origin Synthetic hexapeptide GHRP
Administration Subcutaneous injection, Intravenous
Status Research compound
Mechanism of Action The strongest GH-releasing peptide in its class, activating ghrelin receptors on the pituitary. Uniquely also protects heart tissue from damage and fibrosis independently of its growth hormone effects.
Research Overview Hexarelin (examorelin) is a synthetic hexapeptide growth hormone secretagogue that distinguishes itself from other members of the GHRP family through its dual identity as both the most potent stimulator of GH release among classical hexapeptide GHRPs and a peptide with significant GH-independent cardioprotective properties. Developed in the early 1990s, hexarelin incorporates a 2-methyltryptophan substitution at the second position that enhances binding affinity at the growth hormone secretagogue receptor (GHS-R1a) while also enabling interactions with a distinct cardiac receptor - later identified as the scavenger receptor CD36 - that mediates its cardiovascular protective effects independently of growth hormone release. The cardioprotective actions of hexarelin have been extensively characterized in multiple preclinical models. In isolated perfused heart preparations subjected to ischemia-reperfusion, hexarelin pre-treatment reduced infarct size by up to 75% and significantly improved recovery of contractile function. In chronic heart failure models, hexarelin administration reduced cardiac fibrosis, improved left ventricular ejection fraction, and decreased circulating levels of brain natriuretic peptide (BNP), a biomarker of cardiac stress. Mechanistic studies revealed that hexarelin's cardiac effects involve activation of the PI3K/Akt survival signaling pathway, reduced mitochondrial permeability transition pore opening, and decreased cardiomyocyte apoptosis. The interaction with CD36 appears to modulate fatty acid uptake and metabolism in cardiac tissue, and hexarelin has also been shown to reduce cholesterol accumulation in macrophages, suggesting anti-atherosclerotic properties. Clinical studies in healthy volunteers and GH-deficient patients confirmed hexarelin's potent GH-releasing activity, but also revealed that unlike some other GHRPs, hexarelin shows some degree of tachyphylaxis (reduced response) with chronic administration, potentially due to GHS receptor desensitization. This limitation, combined with the cortisol and prolactin elevation associated with high-dose use, has positioned hexarelin more as a research tool and potential cardioprotective agent than as a primary GH-stimulating therapeutic.

Citations

Published findings on Hexarelin from peer-reviewed journals.

Research Assistant
Hey, I'm the PepSpace research assistant. Ask me anything about peptides and I'll do my best to help.