NOT MEDICAL ADVICE

GHRP-6

Estimated Market Price
$94.99 $109.99
Based on verified supplier pricing for research-grade compounds
GH secretagogue with strong appetite stimulation. Ideal for bulking phases with robust growth hormone output and gastroprotective properties.
How it works

Mimics ghrelin to trigger strong growth hormone release from the pituitary. Also increases appetite and gut motility as a side effect of its ghrelin-like action.

Growth Hormone

Performance

What to Expect
Week 1–2 Appetite increase and GH pulses amplified; deeper sleep. Ravenous hunger 30 min after injection; sleep much deeper.
Week 3–4 Recovery acceleration; subtle body composition shift starting. Recovering faster; body starting to fill out.
Week 5–8 IGF-1 levels elevated; lean mass and fat loss progressing. Gaining lean mass; less fat despite eating more.
Week 9–12 Peak GH secretagogue benefits; assess with bloodwork. Stronger and fuller; body composition clearly improved.

Verified Suppliers

For research purposes only. These suppliers have been independently verified by PepSpace. We do not process sales directly.

PepSpace is not affiliated with any listed supplier
Protocol & Dosage
Typical Dosage 100–300 mcg SC per dose
Administration Subcutaneous injection
Schedule 2–3x daily; 30 min before meals or before bed
Protocol Duration 8–12 weeks
Half-Life ~15-20 minutes
Side Effects & Safety
Tolerability Profile Moderate

Notable side effects likely; manageable with proper awareness

Common Side Effects

  • Intense hunger spike (ghrelin mimetic)~80%
  • Injection site rednessmost users
  • Water retention and bloatingmost users
  • Mild flushingsome users

Less Common

  • Cortisol elevationoccasional
  • Joint stiffnessoccasional
  • Tingling or numbnessoccasional
  • Prolactin elevationoccasional
  • Headacheoccasional

Rare / Serious

  • Blood sugar elevationrare
  • Persistent edemarare

Discontinue If

  • Carpal tunnel symptoms (hand numbness, weakness)
  • Signs of elevated blood sugar (increased thirst, frequent urination)
  • Persistent hunger disrupting diet or daily life

Contraindications

  • Active cancer or tumors
  • Diabetic retinopathy
  • Pregnancy or breastfeeding
  • Obesity with uncontrolled appetite

Data note: Least selective GHRP — raises cortisol, prolactin, and causes strong hunger. Generally replaced by ipamorelin in modern protocols.

Always consult a qualified healthcare professional before use. This information is for research reference only and does not constitute medical advice.

Ask about GHRP-6
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How to Apply

1

Gather

Peptide vial, BAC water, alcohol swabs, insulin syringe

2

Sanitize

Wipe tops of both vials with alcohol swabs

3

Draw

Pull 1–2 mL of BAC water into syringe

4

Add Water

Release water slowly along vial wall, not directly on powder

5

Swirl

Roll between palms until dissolved. Never shake.

6

Store

Refrigerate 2–8°C, use within 30 days

Frequently Asked Questions

Yes. Bacteriostatic water (BAC water) is required to reconstitute lyophilized (freeze-dried) peptides. It contains 0.9% benzyl alcohol which prevents bacterial growth, keeping your reconstituted peptide safe for multiple uses over up to 30 days.

Unreconstituted: store at -20°C (freezer) for long-term, or 2–8°C (fridge) for short-term. After reconstitution: always refrigerate at 2–8°C and use within 30 days. Keep away from direct sunlight.

Results vary by individual and protocol. In research settings, measurable effects are typically observed within 1–4 weeks depending on the specific peptide, dosage, and application. Consult a qualified professional for guidance.

Verified suppliers typically include a full third-party COA verifying purity (99%+), identity, and sterility. We recommend only sourcing from vendors that provide batch-specific testing data.

We list verified suppliers above that have been independently reviewed for product quality, testing transparency, and shipping reliability. Always verify COA data before sourcing.

Compound Profile

Scientific data & classification for GHRP-6

Also Known As Growth Hormone Releasing Peptide-6, GHRP-6, SKF-110679
Classification Hexapeptide · Growth Hormone Secretagogue
Sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula C₄₆H₅₆N₁₂O₆
Molecular Weight 873.01 Da
CAS Number 87616-84-0
Half-Life ~15-20 minutes
Origin Synthetic hexapeptide growth hormone secretagogue
Administration Subcutaneous injection
Status Research compound
Mechanism of Action Mimics ghrelin to trigger strong growth hormone release from the pituitary. Also increases appetite and gut motility as a side effect of its ghrelin-like action.
Research Overview Growth Hormone Releasing Peptide-6 (GHRP-6) is a synthetic hexapeptide that holds historical significance as one of the first peptidic growth hormone secretagogues identified and one of the foundational compounds that led to the discovery of the ghrelin receptor system. Developed in the 1980s by Cyril Bowers at Tulane University through systematic modification of met-enkephalin analogs that unexpectedly stimulated growth hormone release, GHRP-6 was among the first compounds shown to activate what was then an orphan receptor - the growth hormone secretagogue receptor (GHS-R1a), which was subsequently identified as the receptor for ghrelin, the endogenous "hunger hormone" discovered by Kojima and colleagues in 1999. GHRP-6 binds the GHS-R1a receptor on pituitary somatotroph cells, activating a phospholipase C/inositol triphosphate/protein kinase C signaling cascade that is distinct from and synergistic with the adenylyl cyclase/cAMP pathway activated by GHRH. This mechanistic complementarity is the basis for the well-documented synergistic GH release observed when GHRPs are combined with GHRH analogs - co-administration typically produces GH release 3-6 times greater than either peptide alone. However, GHRP-6's non-selective ghrelin mimicry produces several notable off-target effects: significant stimulation of appetite and food intake (through hypothalamic ghrelin receptor activation), mild elevation of cortisol and prolactin (through actions on corticotrophs and lactotrophs), increased gastric motility, and potential cardiovascular effects. These properties distinguish GHRP-6 from later, more selective secretagogues like ipamorelin. In research applications, GHRP-6 has proven invaluable as a pharmacological tool for studying the ghrelin/GHS receptor system and has been used extensively in GH provocation tests for diagnosing growth hormone deficiency, where its ability to reliably stimulate GH release makes it a useful diagnostic agent.

Citations

Published findings on GHRP-6 from peer-reviewed journals.

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